Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28478338 | 1.00 | KDM4E (0.43) | KDM4EHPGDLMNAMAPTALDH1A1 | |
| SCHEMBL17785249 | 0.85 | HCAR3 (0.47) | KDM4EHPGDALDH1A1HCAR3SLC22A12 | |
| SCHEMBL4509480 | 0.76 | SLC22A12 (0.57) | KDM4EHCAR3SLC22A12HTT | |
| SCHEMBL30040324 | 0.76 | SLC22A12 (0.57) | KDM4EHCAR3SLC22A12HTT | |
| SCHEMBL28472713 | 0.75 | KMT2A (0.41) | KDM4EHPGDMAPTALDH1A1CA1 | |
| SCHEMBL28472711 | 0.75 | KMT2A (0.41) | KDM4EHPGDMAPTALDH1A1CA1 | |
| SCHEMBL23559591 | 0.75 | HCAR3 (0.46) | KDM4EHPGDMAPTALDH1A1HCAR3 | |
| SCHEMBL29241328 | 0.75 | HCAR3 (0.46) | KDM4EHPGDLMNAMAPTALDH1A1 | |
| SCHEMBL31632926 | 0.75 | HCAR3 (0.46) | KDM4EHPGDALDH1A1HCAR3SLC22A12 | |
| SCHEMBL30204438 | 0.75 | HCAR3 (0.46) | KDM4EHPGDLMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825595-A | Sodium channel blockers | 山东轩竹医药科技有限公司 | 2020-10-27 | — | — | CN | disclosed |