SCHEMBL28478368

SCHEMBL28478368

O=C1c2cccc(-c3ccccc3)c2C(=O)C1(O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 10/20 0.61
CA2 P00918 10/20 0.61
CA7 P43166 10/20 0.61
CA9 Q16790 10/20 0.61
ALDH1A1 P00352 2/20 0.59
TSHR P16473 1/20 0.59
ALOX12 P18054 1/20 0.59
MAPK1 P28482 1/20 0.59
CASP1 P29466 1/20 0.59
RECQL P46063 1/20 0.59
BACE1 P56817 1/20 0.59
EHMT2 Q96KQ7 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
HDAC4 P56524 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
HNF4A P41235 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4929877 0.76 CA1 (0.41) CA1CA2CA7CA9ALDH1A1
SCHEMBL29350272 0.76 CA1 (1.00) CA1CA2CA7CA9ALDH1A1
SCHEMBL3658029 0.76 CA1 (1.00) CA1CA2CA7CA9ALDH1A1
SCHEMBL17986 0.76 CA1 (1.00) CA1CA2CA7CA9ALDH1A1
SCHEMBL15642543 0.76 CA1 (1.00) CA1CA2CA7CA9ALDH1A1
SCHEMBL24736915 0.74 HDAC4 (0.52) ALDH1A1TSHRMAPK1RECQLBACE1
SCHEMBL29976182 0.74 HDAC4 (0.52) ALDH1A1TSHRMAPK1RECQLBACE1
SCHEMBL11424452 0.74 HDAC4 (0.52) ALDH1A1MAPK1BACE1L3MBTL1HDAC4
SCHEMBL6199820 0.74 CA1 (1.00) CA1CA2CA7CA9ALDH1A1
SCHEMBL8665649 0.74 CA1 (1.00) CA1CA2CA7CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111830015-B Method for quantitatively detecting antibiotics 中国农业科学院农产品加工研究所 2022-12-09 CN disclosed
CN-111830015-A Method for quantitatively detecting antibiotics 中国农业科学院农产品加工研究所 2020-10-27 CN disclosed