Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 14/20 | 1.00 |
| ▸ | CA2 | P00918 | 14/20 | 1.00 |
| ▸ | CA7 | P43166 | 14/20 | 1.00 |
| ▸ | CA9 | Q16790 | 14/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28285608 | 0.80 | CA1 (0.67) | CA1CA2CA7CA9RECQL | |
| SCHEMBL11324259 | 0.78 | CA1 (0.64) | CA1CA2CA7CA9RECQL | |
| SCHEMBL15642543 | 0.78 | CA1 (1.00) | CA1CA2CA7CA9RECQL | |
| SCHEMBL8665649 | 0.76 | CA1 (1.00) | CA1CA2CA7CA9RECQL | |
| SCHEMBL27641878 | 0.76 | CA1 (0.63) | CA1CA2CA7CA9RECQL | |
| SCHEMBL24756654 | 0.75 | CA1 (0.61) | CA1CA2CA7CA9RECQL | |
| SCHEMBL28478368 | 0.74 | CA1 (0.61) | CA1CA2CA7CA9RECQL | |
| SCHEMBL1886422 | 0.74 | CA1 (0.58) | CA1CA2CA7CA9ALDH1A1 | |
| Methyl Alcohol SCHEMBL3930226 | 0.73 | CA1 (0.90) | CA1CA2CA7CA9RECQL | |
| SCHEMBL28294854 | 0.73 | CA1 (0.58) | CA1CA2CA7CA9RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296985-B1 | HETEROPOLYCYCLIC INHIBITORS | QUADRA LOGIC TECH INC (CA) | 2005-06-01 | — | — | EP | disclosed |
| US-20030144294-A1 | Heteropolycyclic inhibitors of protein kinases | QLT INC. (CA) | 2003-07-31 | — | — | US | disclosed |
| EP-1296985-A2 | HETEROPOLYCYCLIC INHIBITORS | Kinetek Pharmaceuticals, Inc. (CA) | 2003-04-02 | — | — | EP | disclosed |
| US-6514972-B2 | Antiproliferative agents | KINETEK PHARMACEUTICALS, INC. (CA) | 2003-02-04 | — | — | US | disclosed |
| US-20020035251-A1 | Heteropolycyclic inhibitors of protein kinases | KINETEK PHARMACEUTICALS, INC. (CA) | 2002-03-21 | — | — | US | disclosed |
| WO-2002002562-A2 | HETEROPOLYCYCLIC INHIBITORS | KINETEK PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | disclosed |
| WO-2001079209-A2 | DIAZAFLUORENONE IL-8 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035251-A1 | Heteropolycyclic inhibitors of protein kinases | DSTYK, PRKCZ, CSNK1A1L | CA1 3734/4885CA2 1684/4885CA7 4283/4885 |
| US-20030144294-A1 | Heteropolycyclic inhibitors of protein kinases | DSTYK, PRKCZ, CSNK1A1L | CA1 3734/4885CA2 1684/4885CA7 4283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.