Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 14/20 | 1.00 |
| ▸ | CA2 | P00918 | 14/20 | 1.00 |
| ▸ | CA7 | P43166 | 14/20 | 1.00 |
| ▸ | CA9 | Q16790 | 14/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15642543 | 0.78 | CA1 (1.00) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL27641878 | 0.76 | CA1 (0.63) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL28285608 | 0.76 | CA1 (0.67) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL6199820 | 0.76 | CA1 (1.00) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL24756654 | 0.75 | CA1 (0.61) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL28478368 | 0.74 | CA1 (0.61) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL14939600 | 0.73 | CA1 (0.57) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL29350272 | 0.73 | CA1 (1.00) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL3658029 | 0.73 | CA1 (1.00) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL17986 | 0.73 | CA1 (1.00) | CA1CA2CA7CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646574-B1 | Ketonic indane derivatives, their preparation and therapeutic application thereof | INNOTHERA LAB SA (FR) | 1998-12-09 | — | — | EP | disclosed |
| EP-0646574-A1 | Ketonic indane derivatives, their preparation and therapeutic application thereof | LABORATOIRE INNOTHERA Société Anonyme (FR) | 1995-04-05 | — | — | EP | disclosed |
| EP-0646579-A1 | Ketonic indane derivatives and heterocyclic analysis and their use in therapy | LABORATOIRE INNOTHERA Société Anonyme (FR) | 1995-04-05 | — | — | EP | disclosed |