Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Adamantane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adamantane SCHEMBL28945080 | 1.00 | GAA (0.50) | GAACYP2C9HSD11B1CA2TSHR | |
| Phosphoric Acid SCHEMBL11162126 | 0.76 | CA2 (0.50) | CA2TSHRSLC34A1 | |
| Phosphoric Acid SCHEMBL30268977 | 0.76 | — | — | |
| Phosphoric Acid SCHEMBL29901834 | 0.76 | CA2 (0.50) | CA2TSHRSLC34A1 | |
| Phosphoric Acid SCHEMBL29386834 | 0.76 | — | — | |
| Phosphoric Acid SCHEMBL3242659 | 0.71 | CA2 (0.46) | CA2SLC34A1 | |
| Phosphoric Acid SCHEMBL443602 | 0.71 | — | — | |
| Phosphoric Acid SCHEMBL439313 | 0.71 | — | — | |
| Phosphoric Acid SCHEMBL17417828 | 0.71 | CA2 (0.46) | CA2SLC34A1 | |
| Phosphoric Acid SCHEMBL7106956 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107955683-B | Multifunctional lubricating oil | 山东一和润滑油有限公司 | 2020-10-13 | — | — | CN | claimed |
| CN-113717774-A | Multifunctional lubricating oil and preparation method thereof | 泗县唯澳生物技术开发有限公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-107955683-B | Multifunctional lubricating oil | 山东一和润滑油有限公司 | 2020-10-13 | — | — | CN | disclosed |
| CN-107955683-B | Multifunctional lubricating oil | 山东一和润滑油有限公司 | 2020-10-13 | — | — | CN | disclosed |