Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.40 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32662972 | 0.92 | RXRA (0.44) | MCL1RXRARXRBRXRGFGFR1 | |
| SCHEMBL28481979 | 0.89 | MCL1 (0.46) | MCL1RXRARXRBRXRGFGFR1 | |
| SCHEMBL23535723 | 0.87 | MCL1 (0.45) | MCL1RXRARXRBRXRGFGFR1 | |
| SCHEMBL29194155 | 0.81 | RXRA (0.47) | MCL1RXRARXRBRXRGFGFR1 | |
| SCHEMBL19029753 | 0.78 | MCL1 (0.45) | MCL1RXRARXRBRXRGFGFR1 | |
| SCHEMBL25167771 | 0.78 | MCL1 (0.45) | MCL1RXRARXRBRXRGFGFR1 | |
| SCHEMBL30867575 | 0.76 | KDM5B (0.42) | MCL1RXRARXRBRXRGFGFR1 | |
| SCHEMBL29194193 | 0.74 | MCL1 (0.40) | MCL1RXRARXRBRXRGFGFR1 | |
| SCHEMBL23535740 | 0.74 | MCL1 (0.47) | MCL1RXRARXRBRXRGFGFR1 | |
| SCHEMBL30041685 | 0.73 | MKNK1 (0.46) | MCL1RXRARXRBRXRGFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776504-B | Metal organic framework material based on low-symmetry pyrazole-carboxylic acid ligand Zn, and preparation method and application thereof | 北京工业大学 | 2020-10-16 | — | — | CN | claimed |
| CN-109776504-B | Metal organic framework material based on low-symmetry pyrazole-carboxylic acid ligand Zn, and preparation method and application thereof | 北京工业大学 | 2020-10-16 | — | — | CN | disclosed |