Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29194155 | 0.92 | RXRA (0.47) | MCL1RXRARXRBRXRGFGFR1 | |
| SCHEMBL28480271 | 0.89 | MCL1 (0.43) | MCL1RXRARXRBRXRGFGFR1 | |
| SCHEMBL23535740 | 0.85 | MCL1 (0.47) | MCL1RXRARXRBRXRGFGFR1 | |
| SCHEMBL32662972 | 0.82 | RXRA (0.44) | MCL1RXRARXRBRXRGFGFR1 | |
| SCHEMBL29194193 | 0.82 | MCL1 (0.40) | MCL1RXRARXRBRXRGFGFR1 | |
| Fluoride SCHEMBL14796503 | 0.76 | ACHE (0.43) | MCL1RXRARXRBRXRGFGFR1 | |
| SCHEMBL5139638 | 0.76 | ACHE (0.43) | MCL1RXRARXRBRXRGFGFR1 | |
| SCHEMBL30041685 | 0.76 | MKNK1 (0.46) | MCL1RXRARXRBRXRGFGFR1 | |
| SCHEMBL32688174 | 0.76 | MCL1 (0.47) | MCL1RXRARXRBRXRGFGFR1 | |
| SCHEMBL25015558 | 0.76 | MCL1 (0.47) | MCL1RXRARXRBRXRGFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776504-B | Metal organic framework material based on low-symmetry pyrazole-carboxylic acid ligand Zn, and preparation method and application thereof | 北京工业大学 | 2020-10-16 | — | — | CN | disclosed |