Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6759607 | 0.91 | DNMT1 (0.44) | HPRT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30617063 | 0.91 | DNMT1 (0.44) | HPRT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27619805 | 0.90 | HPRT1 (0.47) | HPRT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17263921 | 0.82 | PBRM1 (0.40) | ALDH1A1MEN1USP2HPGDKMT2A | |
| SCHEMBL6215591 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MEN1USP2LMNAHPGD | |
| SCHEMBL27467873 | 0.79 | HPRT1 (0.47) | HPRT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| Phthalazine SCHEMBL27577696 | 0.74 | ALDH1A1 (0.49) | HPRT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29381793 | 0.74 | HPRT1 (0.48) | HPRT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5672208 | 0.73 | HPGD (0.44) | HPRT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7345934 | 0.73 | HPRT1 (0.58) | HPRT1ALDH1A1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111417410-A | Glucocorticoid receptor agonists and immunoconjugates thereof | 艾伯维公司 | 2020-07-14 | — | — | CN | disclosed |