SCHEMBL7345934

SCHEMBL7345934

c1ccc2c(c1)ccc1c3c(ccc12)CC3

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 3/20 0.58
ALDH1A1 P00352 3/20 0.50
HSD17B10 Q99714 3/20 0.50
CYP2A6 P11509 1/20 0.50
TSHR P16473 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CYP1A2 P05177 2/20 0.49
MAPT P10636 2/20 0.49
LCK P06239 1/20 0.49
FYN P06241 1/20 0.49
ADORA3 P0DMS8 1/20 0.49
ACHE P22303 1/20 0.49
SLC6A2 P23975 1/20 0.49
AHR P35869 1/20 0.49
PAX8 Q06710 1/20 0.43
HIF1A Q16665 1/20 0.43
CYP1B1 Q16678 1/20 0.43
KDM4E B2RXH2 1/20 0.41
GLA P06280 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL54652 0.89 ALDH1A1 (0.50) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL29481017 0.89 ALDH1A1 (0.50) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL29554780 0.88 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL21176632 0.88 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL27740850 0.88 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL30928215 0.88 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL2089665 0.88 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL1826535 0.88 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL29580834 0.88 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
Phenanthrene SCHEMBL27372954 0.88 HPRT1 (0.54) HPRT1ALDH1A1HSD17B10CYP2A6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118146539-A Crosslinked cycloolefin copolymer, preparation method and application thereof 中国科学院长春应用化学研究所 2024-06-07 CN claimed
CN-118146539-A Crosslinked cycloolefin copolymer, preparation method and application thereof 中国科学院长春应用化学研究所 2024-06-07 CN disclosed
CN-101668742-B Bridged six-membered ring compounds ACTELION PHARMACEUTICALS LTD 2014-04-30 CN disclosed
CN-101668742-A Bridged six-membered ring compounds ACTELION PHARMACEUTICALS LTD 2010-03-10 CN disclosed
CN-1203854-C Compositions with improved delivery of active ingredients PROCTER & GAMBLE (US) 2005-06-01 CN disclosed
CN-1346270-A Compositions having improved stability PROCTER & GAMBER CO (US) 2002-04-24 CN disclosed
CN-1336822-A Compositions having improved stability PROCTER & GAMBLE (US) 2002-02-20 CN disclosed
CN-1336823-A Compositions with improved delivery of active ingredients PROCTER & GAMBLE (US) 2002-02-20 CN disclosed
EP-0555411-A1 DEXTROMETHORPHAN ANTITUSSIVE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1993-08-18 EP disclosed
WO-1992007559-A1 DEXTROMETHORPHAN ANTITUSSIVE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1992-05-14 WO disclosed