SCHEMBL28480429

SCHEMBL28480429

CCOP(=O)(OC=Cc1ccccc1)OCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 1/20 0.50
NPSR1 Q6W5P4 2/20 0.43
RELA Q04206 1/20 0.43
KCNH2 Q12809 1/20 0.42
AOX1 Q06278 1/20 0.41
POLB P06746 1/20 0.40
ACHE P22303 1/20 0.40
TSHR P16473 1/20 0.40
ALDH1A1 P00352 2/20 0.39
MAPT P10636 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 1/20 0.39
CYP1A2 P05177 1/20 0.39
GLA P06280 1/20 0.39
CYP3A4 P08684 1/20 0.39
GAA P10253 1/20 0.39
CYP2C9 P11712 1/20 0.39
HPGD P15428 1/20 0.39
ALOX12 P18054 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28572216 0.83 NR1I2 (0.51) NR1I2NPSR1RELAKCNH2AOX1
SCHEMBL25286050 0.83 NR1I2 (0.47) NR1I2NPSR1RELAKCNH2AOX1
SCHEMBL1398210 0.83 MAOB (0.44) ALDH1A1MAPTCYP1A2GLACYP2C9
SCHEMBL28030371 0.80 TRPA1 (0.42) ALDH1A1MEN1KMT2ACYP1A2GLA
Ether SCHEMBL16671539 0.80 RELA (0.41) NR1I2RELAALDH1A1KDM4ECYP1A2
SCHEMBL28790160 0.79 RELA (0.42) NR1I2RELAALDH1A1MEN1KMT2A
SCHEMBL1876079 0.78 NR1I2 (0.49) NR1I2NPSR1RELAKCNH2AOX1
SCHEMBL1876077 0.78 NR1I2 (0.49) NR1I2NPSR1RELAKCNH2AOX1
SCHEMBL28583393 0.77 MAOB (0.44) NR1I2NPSR1KCNH2AOX1POLB
Triethyl Phosphate SCHEMBL21823232 0.77 NR1I2 (0.54) NR1I2NPSR1RELAKCNH2AOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107952454-B Nano catalyst Fe with magnetic core-shell structure3O4@ Te @ Pd and preparation method thereof 浙江医药高等专科学校 2020-10-20 CN disclosed