Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28483815 | 0.85 | RECQL (0.40) | ALDH1A1RAB9ATSHRGAAMAPK1 | |
| SCHEMBL28479383 | 0.85 | HSPB1 (0.48) | ALDH1A1RAB9ATSHRGAAMAPK1 | |
| SCHEMBL28484102 | 0.85 | MAPT (0.43) | ALDH1A1RAB9AGAAMAPK1MAPT | |
| SCHEMBL28902472 | 0.84 | KMT2A (0.48) | ALDH1A1RAB9AKDM4EGAAMAPK1 | |
| SCHEMBL28475352 | 0.83 | MAPT (0.42) | ALDH1A1RAB9AKDM4EGAAMAPK1 | |
| SCHEMBL28478727 | 0.82 | MAPT (0.38) | ALDH1A1RAB9ATSHRKDM4EGAA | |
| SCHEMBL28484057 | 0.81 | RECQL (0.40) | ALDH1A1RAB9AKDM4EGAAMAPT | |
| SCHEMBL28482830 | 0.78 | MAPK1 (0.56) | ALDH1A1RAB9AGAAMAPK1MAPT | |
| SCHEMBL28477045 | 0.75 | HSP90AA1 (0.44) | ALDH1A1RAB9ATSHRKDM4EGAA | |
| SCHEMBL6550416 | 0.73 | TSHR (0.75) | ALDH1A1RAB9ATSHRKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108164397-B | Catechol derivative and its preparation method | 暨南大学 | 2020-11-13 | — | — | CN | disclosed |