Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28479383 | 0.85 | HSPB1 (0.48) | MAPTLMNAMAPK1CYP1A2CYP3A4 | |
| SCHEMBL28483815 | 0.85 | RECQL (0.40) | MAPTLMNAMAPK1CYP1A2CYP3A4 | |
| SCHEMBL28480484 | 0.85 | ALDH1A1 (0.43) | MAPTLMNAMAPK1RECQLRAB9A | |
| SCHEMBL28902472 | 0.84 | KMT2A (0.48) | MAPTLMNAMAPK1RECQLRAB9A | |
| SCHEMBL28475352 | 0.83 | MAPT (0.42) | MAPTLMNAMAPK1CYP1A2CYP2C19 | |
| SCHEMBL28478727 | 0.82 | MAPT (0.38) | MAPTLMNAMAPK1CYP1A2CYP3A4 | |
| SCHEMBL28484057 | 0.81 | RECQL (0.40) | MAPTLMNACYP1A2RECQLRAB9A | |
| SCHEMBL28888427 | 0.79 | KMT2A (0.42) | MAPTLMNAMAPK1CYP1A2CYP3A4 | |
| SCHEMBL11338058 | 0.73 | KDM4E (0.58) | MAPTLMNAMAPK1RAB9AMEN1 | |
| SCHEMBL28485005 | 0.73 | HTT (0.35) | MAPTLMNAMAPK1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108164397-B | Catechol derivative and its preparation method | 暨南大学 | 2020-11-13 | — | — | CN | disclosed |