Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28473635 | 0.91 | L3MBTL1 (0.46) | TDP1L3MBTL1ALDH1A1POLBMEN1 | |
| SCHEMBL28472696 | 0.84 | SCN9A (0.51) | PKMGAA | |
| SCHEMBL28475260 | 0.80 | TDP1 (0.46) | TDP1L3MBTL1ALDH1A1POLBMEN1 | |
| SCHEMBL28473486 | 0.77 | SCN9A (0.41) | L3MBTL1MEN1KMT2AKDM4EMRGPRX4 | |
| SCHEMBL28472217 | 0.72 | GRM4 (0.49) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL28475433 | 0.72 | GAA (0.45) | TDP1L3MBTL1ALDH1A1POLBMEN1 | |
| SCHEMBL28366479 | 0.71 | TDP1 (0.58) | TDP1L3MBTL1ALDH1A1POLBMEN1 | |
| SCHEMBL14271520 | 0.70 | SLC22A12 (0.36) | ALDH1A1LMNAKDM4E | |
| SCHEMBL4261343 | 0.69 | SLC22A12 (0.60) | ALDH1A1MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL30204934 | 0.69 | SCN9A (0.46) | L3MBTL1ALDH1A1MEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825595-A | Sodium channel blockers | 山东轩竹医药科技有限公司 | 2020-10-27 | — | — | CN | disclosed |