Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28475260 | 0.91 | TDP1 (0.46) | GAALMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28482013 | 0.83 | SCN9A (0.52) | — | |
| SCHEMBL28473635 | 0.81 | L3MBTL1 (0.46) | GAALMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28475542 | 0.74 | MAPT (0.49) | GAALMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL23535685 | 0.72 | ALDH1A1 (0.40) | GAASMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL30040757 | 0.72 | ALDH1A1 (0.40) | GAASMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL28470048 | 0.72 | MAPT (0.56) | GAALMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28480695 | 0.72 | TDP1 (0.47) | GAALMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28470424 | 0.71 | KDM4E (0.42) | GAASMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL30204298 | 0.70 | NPC1 (0.54) | GAALMNASMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825595-A | Sodium channel blockers | 山东轩竹医药科技有限公司 | 2020-10-27 | — | — | CN | disclosed |