SCHEMBL28480784

SCHEMBL28480784

[CH2]OC(C)(C=C)CCC=C(C)C

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 0.57
HIF1A Q16665 4/20 0.41
EPAS1 Q99814 4/20 0.41
TSHR P16473 1/20 0.36
CYP3A4 P08684 2/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
MAPK1 P28482 1/20 0.33
CHRNA7 P36544 1/20 0.33
STAT3 P40763 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL988359 0.86 ALOX15 (0.59) ALOX15HIF1AEPAS1TSHRCYP3A4
SCHEMBL454435 0.84 ALOX15 (0.57) ALOX15HIF1AEPAS1TSHRCYP3A4
SCHEMBL8160898 0.84 ALOX15 (0.57) ALOX15HIF1AEPAS1TSHRCYP3A4
SCHEMBL11217537 0.83 ALOX15 (0.52) ALOX15HIF1AEPAS1TSHRCYP3A4
SCHEMBL27995055 0.82 ALOX15 (0.55) ALOX15HIF1AEPAS1TSHRCYP3A4
SCHEMBL8374951 0.82 ALOX15 (0.55) ALOX15HIF1AEPAS1TSHRKMT2A
SCHEMBL164899 0.81 ALOX15 (0.53) ALOX15HIF1AEPAS1TSHR
SCHEMBL11293671 0.81 ALOX15 (0.53) ALOX15HIF1AEPAS1TSHR
SCHEMBL28452346 0.81 ALOX15 (0.53) ALOX15HIF1AEPAS1TSHR
SCHEMBL3746964 0.79 ALOX15 (0.52) ALOX15HIF1AEPAS1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114306171-A Topical skin compositions and uses thereof 玫琳凯有限公司 2022-04-12 CN disclosed
CN-108403521-B Topical skin compositions and uses thereof 玫琳凯有限公司 2022-02-11 CN disclosed
CN-106074278-B Topical skin care formulations comprising plant extracts 玫琳凯有限公司 2020-11-27 CN disclosed