SCHEMBL454435

SCHEMBL454435

C=CC(C)(CCC=C(C)C)OC

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 5/20 0.57
HIF1A Q16665 4/20 0.44
EPAS1 Q99814 4/20 0.44
TSHR P16473 1/20 0.36
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPK1 P28482 1/20 0.30
CHRNA7 P36544 1/20 0.30
STAT3 P40763 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11665836 0.90 ALOX15 (0.64) ALOX15KMT2AMEN1CYP3A4
SCHEMBL11665834 0.90 ALOX15 (0.64) ALOX15KMT2AMEN1CYP3A4
SCHEMBL988359 0.86 ALOX15 (0.59) ALOX15HIF1AEPAS1TSHRKMT2A
SCHEMBL8375220 0.85 ALOX15 (0.50) ALOX15HIF1AEPAS1TSHR
SCHEMBL28480784 0.84 ALOX15 (0.57) ALOX15HIF1AEPAS1TSHRKMT2A
SCHEMBL8160898 0.84 ALOX15 (0.57) ALOX15HIF1AEPAS1TSHRKMT2A
SCHEMBL8374951 0.82 ALOX15 (0.55) ALOX15HIF1AEPAS1TSHRKMT2A
SCHEMBL27995055 0.82 ALOX15 (0.55) ALOX15HIF1AEPAS1TSHRKMT2A
SCHEMBL164899 0.81 ALOX15 (0.53) ALOX15HIF1AEPAS1TSHR
SCHEMBL28452346 0.81 ALOX15 (0.53) ALOX15HIF1AEPAS1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4096618-B1 A MIXTURE COMPRISING 1,2-ALKANEDIOLS SYMRISE AG (DE) 2025-01-29 EP claimed
EP-4438065-A2 A MIXTURE COMPRISING 1,2-ALKANEDIOLS Symrise AG (DE) 2024-10-02 EP claimed
CN-116490160-A A mixture containing 1, 2-alkanediol 西姆莱斯股份公司 2023-07-25 CN claimed
EP-4096618-A1 A MIXTURE COMPRISING 1,2-ALKANEDIOLS Symrise AG (DE) 2022-12-07 EP claimed
US-20220364016-A1 PERFUME OIL MIXTURE SYMRISE AG (DE) 2022-11-17 US claimed
WO-2022122143-A1 A MIXTURE COMPRISING 1,2-ALKANEDIOLS SYMRISE AG (DE) 2022-06-16 WO claimed
CN-107257844-B Synergistic perfuming composition 弗门尼舍有限公司 2021-09-14 CN claimed
US-10308895-B2 Synergistic perfuming composition FIRMENICH SA (CH) 2019-06-04 US claimed
US-20190155975-A9 Antiperspirant and Deodorant Compositions Comprising Malodor Reduction Compositions THE PROCTER & GAMBLE COMPANY 2019-05-23 US claimed
US-10240108-B2 Particles for malodor reduction THE PROCTER & GAMBLE COMPANY (US) 2019-03-26 US claimed
US-8318222-B2 Topical skin care formulation MARY KAY, INC. (US) 2012-11-27 US claimed
US-8039011-B2 A temperature change composition including a neurosensory component, e.g., menthol, and a first phase change component having a first phase change temperature between 15-40 degrees C., e.g., hydrocarbon, wax; encapsulated evaporative cooling agent; refreshing; durability; receptivity with other skin item KIMBERLY-CLARK WORLDWIDE, INC. (US) 2011-10-18 US claimed
US-20110206793-A1 TOPICAL SKIN CARE FORMULATION MARY KAY INC. (US) 2011-08-25 US claimed
EP-2207524-A2 SKIN COOLING COMPOSITION Kimberly-Clark Worldwide, Inc. (US) 2010-07-21 EP claimed
EP-2059229-A2 SKIN COOLING COMPOSITIONS Kimberly-Clark Worldwide, Inc. (US) 2009-05-20 EP claimed
WO-2009057000-A2 SKIN COOLING COMPOSITION KIMBERLY-CLARK WORLDWIDE, INC. (US) 2009-05-07 WO claimed
US-20090110656-A1 Skin cooling composition KIMBERLY-CLARK WORLDWIDE, INC. 2009-04-30 US claimed
WO-2008044154-A2 SKIN COOLING COMPOSITIONS KIMBERLY-CLARK WORLDWIDE, INC. (US) 2008-04-17 WO claimed
US-20080085290-A1 Skin cooling compositions KIMBERLY-CLARK WORLDWIDE, INC. 2008-04-10 US claimed
US-20060040218-A1 Terpene ether solvents WYATT MARION F 2006-02-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10308895-B2 Synergistic perfuming composition PIR, TRPA1, CAPZB ALOX15 242/4885HIF1A 984/4885EPAS1 1698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.