SCHEMBL2848083

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11810315	0.84	TDP1 (0.50)	TDP1ALDH1A1HTTSMN1; SMN2TSHR
	SCHEMBL1918973	0.83	GAA (0.50)	TDP1ALDH1A1HTTSMN1; SMN2TSHR
	SCHEMBL17560071	0.81	TDP1 (0.50)	TDP1ALDH1A1HTTSMN1; SMN2TSHR
	SCHEMBL4503248	0.80	TDP1 (0.59)	TDP1ALDH1A1HTTTSHRCYP3A4
	SCHEMBL12488017	0.79	CFTR (0.42)	ALDH1A1HTTTSHRCYP3A4CFTR
	SCHEMBL25455691	0.78	CFTR (0.46)	ALDH1A1TSHRCYP3A4CFTRKDM4E
	SCHEMBL30280800	0.78	CFTR (0.46)	TDP1ALDH1A1TSHRCYP3A4KMT2A
	SCHEMBL1920431	0.78	CFTR (0.46)	TDP1ALDH1A1TSHRCYP3A4KMT2A
	SCHEMBL28406275	0.77	PDGFRB (0.53)	TDP1ALDH1A1HTTSMN1; SMN2CYP3A4
	SCHEMBL256739	0.76	TDP1 (0.62)	TDP1ALDH1A1HTTSMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.