Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1920431 | 1.00 | CFTR (0.46) | CFTRPDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL25455691 | 0.88 | CFTR (0.46) | CFTRKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL3187202 | 0.85 | KDM4E (0.48) | CFTRPDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL1764082 | 0.85 | CA12 (0.46) | CFTRPDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL20802859 | 0.85 | CA12 (0.50) | CFTRKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL17239556 | 0.83 | CFTR (0.43) | CFTRALDH1A1MAPTHPGDGAA | |
| SCHEMBL20129708 | 0.83 | SOS1 (0.44) | CFTRPDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL12488367 | 0.83 | CFTR (0.43) | CFTRPDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL1918973 | 0.83 | GAA (0.50) | CFTRKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL15543856 | 0.83 | CFTR (0.46) | CFTRPDGFRBFGFR1PDGFRAFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116802181-A | Triazolopyridine compounds as kinase inhibitors | 百时美施贵宝公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |