SCHEMBL28480830

SCHEMBL28480830

O=C(O)NC1(F)CCCC1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23573552 0.69 DGAT1 (0.34)
SCHEMBL22310672 0.68 FFAR3 (0.38) CYP2C19
SCHEMBL3823906 0.68 CYP2C19 (0.34) CYP2C19
SCHEMBL18125955 0.68 ALDH1A1 (0.41) CYP2C19
SCHEMBL11663692 0.68 MME (0.32) CYP2C19
SCHEMBL16333537 0.67 CYP2C19 (0.34) CYP2C19
SCHEMBL477423 0.67 HDAC4 (0.38) CYP2C19
SCHEMBL8889211 0.67 CYP2C19 (0.33) CYP2C19
SCHEMBL18183669 0.67 CYP2C19 (0.33) CYP2C19
SCHEMBL10808711 0.67 ALDH1A1 (0.40) CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111825654-A Phenylmethylene piperidine derivatives, preparation method, intermediates and uses thereof 北京酷瓴生物技术有限公司 2020-10-27 CN disclosed