SCHEMBL2848151

SCHEMBL2848151

BC(c1ccc(C(B)P(C23CC4CC(C2)CC(C(C)(C)C)(C4)C3)C23CC4CC(C2)CC(C(C)(C)C)(C4)C3)cc1)P(C12CC3CC(C1)CC(C(C)(C)C)(C3)C2)C12CC3CC(C1)CC(C(C)(C)C)(C3)C2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5736685 0.93 SIGMAR1 (0.34)
SCHEMBL5471270 0.86 GRIN2D (0.31)
SCHEMBL2850584 0.78 SIGMAR1 (0.35)
SCHEMBL1735134 0.71
SCHEMBL2826953 0.70 SIGMAR1 (0.41)
SCHEMBL4234173 0.70 GRIN1 (0.37)
SCHEMBL14340464 0.69 GRIN2D (0.32)
SCHEMBL5734637 0.68 HSD11B1 (0.34)
SCHEMBL4061204 0.66 SIGMAR1 (0.34)
SCHEMBL5734633 0.62 GRIN2D (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2243549-B1 A CATALYST SYSTEM LUCITE INT UK LTD (GB) 2020-09-02 EP disclosed
US-9802185-B2 Catalyst system LUCITE INTERNATIONAL UK LIMITED (GB) 2017-10-31 US disclosed
US-20150321186-A1 CATALYST SYSTEM Mitsubishi Chemical UK Limited (GB) 2015-11-12 US disclosed
EP-2243548-B1 A CATALYST SYSTEM LUCITE INT UK LTD (GB) 2015-11-11 EP disclosed
US-9040445-B2 Catalyst system LUCITE INTERNATIONAL UK LIMITED (GB) 2015-05-26 US disclosed
EP-1713582-B1 A CATALYST SYSTEM LUCITE INT UK LTD (GB) 2013-11-06 EP disclosed
EP-2243549-A1 A catalyst system Lucite International UK Limited (GB) 2010-10-27 EP disclosed
EP-2243548-A1 A catalyst system Lucite International UK Limited (GB) 2010-10-27 EP disclosed
US-20070282124-A1 Catalyst System LUCENT INTERNATIONAL UK LIMITED (GB) 2007-12-06 US disclosed