Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6035274 | 0.83 | CACNA1B (0.55) | MAOBCACNA1BPKMNR4A2PDK1 | |
| SCHEMBL7798087 | 0.82 | CACNA1B (0.50) | CACNA1BSMPD1PTGES | |
| SCHEMBL2240019 | 0.82 | PDK1 (0.54) | MAOBCACNA1BPKMNR4A2PDK1 | |
| SCHEMBL9084746 | 0.82 | PKM (0.55) | MAOBCACNA1BPKMNR4A2PDK1 | |
| SCHEMBL27278489 | 0.80 | MAOB (0.46) | MAOBCACNA1BPKMNR4A2PDK1 | |
| SCHEMBL19770149 | 0.79 | CACNA1B (0.54) | MAOBCACNA1BPKMNR4A2PDK1 | |
| SCHEMBL9087283 | 0.79 | CACNA1B (0.51) | MAOBCACNA1BPKMNR4A2PDK1 | |
| SCHEMBL9265354 | 0.77 | PKM (0.58) | MAOBCACNA1BPKMNR4A2PDK1 | |
| SCHEMBL31625684 | 0.77 | CACNA1B (0.46) | MAOBCACNA1BPKMNR4A2PDK1 | |
| SCHEMBL30768512 | 0.76 | MAOB (0.50) | MAOBCACNA1BPKMNR4A2PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138901-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS, DERIVATIVES THEREOF, AND RELATED METHODS OF USE | BIOGEN IDEC MA INC (US) | 2010-12-02 | — | — | WO | disclosed |