Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.59 |
| ▸ | DRD4 | P21917 | 2/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.59 |
| ▸ | DRD3 | P35462 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | KCNA3 | P22001 | 8/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CCR1 | P32246 | 3/20 | 0.47 |
| ▸ | CCR3 | P51677 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046070 | 0.88 | DRD2 (0.56) | DRD2DRD4OPRM1DRD3CYP2D6 | |
| SCHEMBL6258542 | 0.87 | DRD2 (0.68) | DRD2DRD4OPRM1DRD3CYP2D6 | |
| SCHEMBL2066381 | 0.83 | ATM (0.55) | DRD2DRD4OPRM1DRD3CYP2D6 | |
| SCHEMBL1508086 | 0.80 | CCR1 (0.42) | DRD2DRD4OPRM1DRD3CYP2D6 | |
| SCHEMBL16619486 | 0.79 | DRD2 (0.57) | DRD2DRD4OPRM1DRD3CYP2D6 | |
| SCHEMBL930701 | 0.79 | DRD2 (0.59) | DRD2DRD4OPRM1DRD3CYP2D6 | |
| SCHEMBL12440029 | 0.79 | DRD2 (0.59) | DRD2DRD4OPRM1DRD3CYP2D6 | |
| SCHEMBL1341963 | 0.79 | DRD2 (0.59) | DRD2DRD4OPRM1DRD3CYP2D6 | |
| SCHEMBL4014770 | 0.79 | DRD2 (0.65) | DRD2DRD4OPRM1DRD3CYP2D6 | |
| SCHEMBL2312446 | 0.79 | DRD2 (0.59) | DRD2DRD4OPRM1DRD3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104614468-B | Method for separating imidafenacin and related substances thereof by high performance liquid chromatography | 北京万全德众医药生物技术有限公司 | 2020-11-03 | — | — | CN | claimed |
| CN-104614468-B | Method for separating imidafenacin and related substances thereof by high performance liquid chromatography | 北京万全德众医药生物技术有限公司 | 2020-11-03 | — | — | CN | disclosed |