Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PMM2 | O15305 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4243521 | 0.74 | ALDH1A1 (0.59) | ALDH1A1HSP90AA1MAPK9MAPK10CYP19A1 | |
| SCHEMBL28479977 | 0.72 | MGLL (0.47) | ALDH1A1POLBGAAMEN1KMT2A | |
| SCHEMBL8303359 | 0.71 | MAPT (0.46) | ALDH1A1RAB9APOLBNPC1SMN1; SMN2 | |
| SCHEMBL28477611 | 0.70 | ALDH1A1 (0.46) | ALDH1A1POLBSMN1; SMN2GAAHPGD | |
| SCHEMBL3698008 | 0.70 | ALDH1A1 (0.42) | ALDH1A1RAB9ANPC1SMN1; SMN2GAA | |
| SCHEMBL31310569 | 0.67 | BIRC5 (0.61) | ALDH1A1HSP90AA1MAPK9MAPK10CYP19A1 | |
| SCHEMBL6190919 | 0.67 | BIRC5 (0.61) | ALDH1A1HSP90AA1MAPK9MAPK10CYP19A1 | |
| SCHEMBL22522557 | 0.67 | ALDH1A1 (0.46) | ALDH1A1HSP90AA1MAPK9MAPK10CYP19A1 | |
| SCHEMBL30462932 | 0.67 | ALDH1A1 (0.46) | ALDH1A1HSP90AA1MAPK9MAPK10CYP19A1 | |
| SCHEMBL11738433 | 0.67 | ALDH1A1 (0.46) | ALDH1A1HSP90AA1MAPK9MAPK10CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111892528-B | Preparation method of 7-amide indole compound | 温州医科大学 | 2022-01-04 | — | — | CN | disclosed |
| CN-111892528-A | Preparation method of 7-amide indole compound | 温州医科大学 | 2020-11-06 | — | — | CN | disclosed |