Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 7/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FER | P16591 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | S100A4 | P26447 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16163130 | 0.82 | LMNA (0.43) | TSHRLMNATNKS2MAOAMAOB | |
| SCHEMBL28432130 | 0.73 | TNKS2 (0.33) | TSHRLMNATNKS2NOS2 | |
| SCHEMBL6557130 | 0.73 | TSHR (0.50) | TSHRLMNATNKS2MAOAMAOB | |
| SCHEMBL19568178 | 0.73 | TSHR (0.50) | TSHRLMNATNKS2MAOAMAOB | |
| SCHEMBL28402527 | 0.72 | HPGD (0.44) | LMNATNKS2MAOAMAOBKMT2A | |
| SCHEMBL21627156 | 0.70 | LMNA (0.38) | TSHRLMNATNKS2MAOAMAOB | |
| SCHEMBL29260588 | 0.70 | GAA (0.33) | TNKS2KMT2AMEN1L3MBTL1NOS2 | |
| SCHEMBL19492450 | 0.70 | TSHR (0.47) | TSHRLMNATNKS2MAOAMAOB | |
| SCHEMBL31739367 | 0.70 | TSHR (0.47) | TSHRLMNATNKS2MAOAMAOB | |
| SCHEMBL5807797 | 0.70 | LMNA (0.47) | TSHRLMNATNKS2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111875532-A | Preparation method of 4-bromo-3-hydroxy-3-difluorobenzenesulfonyl-1-methylindoline-2-one compound | 上海应用技术大学 | 2020-11-03 | — | — | CN | disclosed |