SCHEMBL284829

SCHEMBL284829

COc1ncnc2[nH]cnc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.52
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
ESR1 P03372 1/20 0.35
MAPT P10636 2/20 0.33
ABL1 P00519 1/20 0.33
RAD52 P43351 1/20 0.33
RIN1 Q13671 1/20 0.33
RET P07949 1/20 0.33
MKNK1 Q9BUB5 1/20 0.33
MKNK2 Q9HBH9 1/20 0.33
RAB9A P51151 2/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
CSNK2A1 P68400 1/20 0.32
DYRK1A Q13627 1/20 0.32
CSNK2A3 Q8NEV1 1/20 0.32
LMNA P02545 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2940695 0.82 PDPK1 (0.36) PDPK1LMNATRPA1
SCHEMBL3388862 0.81 KDM4E (0.40) PDPK1MAPTMKNK2RAB9ACSNK2A1
6-[(Isopropyl)Oxy]Purine SCHEMBL8939256 0.79 CDK2 (0.44) PDPK1TTBK1TTBK2
SCHEMBL22639807 0.77 CDK1 (0.48) PDPK1CYP1A2CYP2C19MEN1KMT2A
SCHEMBL2938606 0.77 MAP3K7 (0.37) PDPK1
SCHEMBL17924977 0.77 PDPK1 (0.34) PDPK1ESR1
SCHEMBL12270784 0.77 MAP3K7 (0.50)
Methylguanine SCHEMBL29968306 0.76 CDK1 (0.41) PDPK1
Methylguanine SCHEMBL1336757 0.76 CDK1 (0.41) PDPK1
SCHEMBL13369897 0.75 PDPK1 (0.33) PDPK1MKNK2CSNK2A1DYRK1ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 639 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4560315-A2 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES F. Hoffmann-La Roche AG (CH) 2025-05-28 EP claimed
CN-118782152-B Organic heterocyclic biomarker for wild and cultivated four-large family fish population and application thereof 中国水产科学研究院长江水产研究所 2025-05-20 CN claimed
EP-3980554-B1 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES HOFFMANN LA ROCHE (CH) 2025-03-26 EP claimed
CN-118782152-A Organic heterocyclic biomarker for wild and cultivated four-large family fish population and application thereof 中国水产科学研究院长江水产研究所 2024-10-15 CN claimed
CN-113582245-B Preparation method of porous quaternary precursor inside 南通金通储能动力新材料有限公司 2023-11-14 CN claimed
CN-113735190-B Small-particle ternary precursor and preparation method thereof 南通金通储能动力新材料有限公司 2023-07-14 CN claimed
EP-3131914-B1 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV IDENIX PHARMACEUTICALS LLC (US) 2023-05-10 EP claimed
CN-115968815-A Induction method for efficiently producing full-male nibea albiflora triploid 浙江省海洋水产研究所 2023-04-18 CN claimed
US-20220333079-A1 GENETICALLY MODIFIED NK CELL LINE TRANSDUCED WITH GENE ENCODING NOVEL CHIMERIC ANTIGEN RECEPTOR AND USE THEREOF SLBiGen, Inc. (KR) 2022-10-20 US claimed
EP-4032972-A1 GENETICALLY MODIFIED NK CELL LINE TRANSDUCED WITH GENE ENCODING NOVEL CHIMERIC ANTIGEN RECEPTOR AND USE THEREOF Slbigen Inc. (KR) 2022-07-27 EP claimed
US-5817799-A 2'-Fluorofuranosyl derivatives and methods for preparing 2'-fluoropyrimidine and 2'-fluoropurine nucleosides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1998-10-06 US claimed
WO-1998039334-A1 DNA GLYCOSYLASE INHIBITORS, AND USES RELATED THERETO PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1998-09-11 WO claimed
EP-0797676-A2 RECOMBINANT ADENOVIRAL VECTOR AND METHODS OF USE CANJI, Inc. (US) 1997-10-01 EP claimed
EP-0540686-B1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES US COMMERCE (US) 1995-08-30 EP claimed
EP-0365556-B1 NUCLEOSIDE ANALOGUES GENENTECH INC (US) 1995-07-12 EP claimed
WO-1995011984-A2 RECOMBINANT ADENOVIRAL VECTOR AND METHODS OF USE CANJI, INC. (US) 1995-05-04 WO claimed
EP-0540686-A4 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES US COMMERCE (US) 1993-05-26 EP claimed
EP-0540686-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES. US COMMERCE (US) 1993-05-12 EP claimed
US-5118800-A Oligonucleotides possessing a primary amino group in the terminal nucleotide CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1992-06-02 US claimed
WO-1992001700-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1992-02-06 WO claimed