Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.43 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27595241 | 0.93 | SOAT1 (0.57) | SOAT1MEN1FAAHTP53CYP1A2 | |
| Octadecanoic Acid Amide SCHEMBL27994152 | 0.93 | SOAT1 (0.57) | SOAT1MEN1FAAHTP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL28807747 | 0.91 | SOAT1 (0.55) | SOAT1MEN1FAAHTP53CYP1A2 | |
| Palmitamide SCHEMBL28029273 | 0.91 | SOAT1 (0.55) | SOAT1MEN1FAAHTP53CYP1A2 | |
| Palmitamide SCHEMBL3831146 | 0.91 | SOAT1 (0.55) | SOAT1MEN1FAAHTP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL1705678 | 0.91 | SOAT1 (0.55) | SOAT1MEN1FAAHTP53CYP1A2 | |
| Tetradecanamide SCHEMBL4201776 | 0.91 | SOAT1 (0.55) | SOAT1MEN1FAAHTP53CYP1A2 | |
| Octadecanoic Acid Amide SCHEMBL5346586 | 0.91 | SOAT1 (0.55) | SOAT1MEN1FAAHTP53CYP1A2 | |
| SCHEMBL28118922 | 0.90 | SOAT1 (0.45) | SOAT1MEN1FAAHTP53CYP1A2 | |
| Octadecanoic Acid Amide SCHEMBL28799777 | 0.89 | SOAT1 (0.53) | SOAT1MEN1FAAHTP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111888374-A | Microbial killing composition and preparation method thereof | 福安药业集团重庆礼邦药物开发有限公司 | 2020-11-06 | — | — | CN | claimed |
| CN-111888374-A | Microbial killing composition and preparation method thereof | 福安药业集团重庆礼邦药物开发有限公司 | 2020-11-06 | — | — | CN | disclosed |