Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | GAPDH | P04406 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3194321 | 0.72 | DAO (0.35) | GAA | |
| SCHEMBL18796809 | 0.69 | — | — | |
| SCHEMBL5765529 | 0.68 | KMT2A (0.50) | SMN1; SMN2MEN1KMT2ATSHRGAA | |
| SCHEMBL4792068 | 0.68 | BRD4 (0.43) | SMN1; SMN2GAA | |
| SCHEMBL2012149 | 0.68 | MEN1 (0.53) | SMN1; SMN2MEN1KMT2AGAAHPGD | |
| SCHEMBL19477810 | 0.67 | MAPK10 (0.53) | SMN1; SMN2MEN1KMT2AGAAPIK3CD | |
| SCHEMBL10972199 | 0.67 | GOT1 (0.47) | PIK3CAMTOR | |
| SCHEMBL28457161 | 0.67 | — | — | |
| SCHEMBL4667411 | 0.67 | SCN9A (0.46) | MEN1KMT2ABACE1RAB9AALDH1A1 | |
| SCHEMBL29463913 | 0.67 | MAPK10 (0.53) | SMN1; SMN2MEN1KMT2AGAAPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112074515-B | Cyclic compounds as LPA antagonists isoxazoles of hexyl acid | 百时美施贵宝公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-112074515-A | Cyclohexyl acid isoxazoles as LPA antagonists | 百时美施贵宝公司 | 2020-12-11 | — | — | CN | disclosed |