Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.37 |
| ▸ | LIPC | P11150 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 2/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28478735 | 0.93 | FFAR1 (0.37) | LIPGLIPCFFAR1HRH1KCNH2 | |
| SCHEMBL28484478 | 0.92 | LIPG (0.35) | LIPGLIPCFFAR1HRH1KCNH2 | |
| SCHEMBL28478853 | 0.90 | SCD (0.40) | HRH1KCNH2SCDSCN9A | |
| SCHEMBL28478976 | 0.85 | HRH1 (0.36) | LIPGFFAR1HRH1KCNH2MLNR | |
| SCHEMBL28477484 | 0.85 | SCD (0.35) | FFAR1KCNH2SCDSCN9A | |
| SCHEMBL28477481 | 0.83 | SCN9A (0.39) | KCNH2SCN9A | |
| SCHEMBL28901684 | 0.83 | SCN9A (0.39) | LIPGLIPCKCNH2SCDSCN9A | |
| SCHEMBL28478975 | 0.83 | RBP4 (0.36) | FFAR1HRH1KCNH2SCDSCN9A | |
| SCHEMBL28485631 | 0.83 | HRH1 (0.38) | FFAR1HRH1KCNH2SCN9ACTSL | |
| SCHEMBL19640426 | 0.82 | FFAR1 (0.44) | LIPGLIPCFFAR1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428730-B | 1,3, 5-triazinyl PI3K inhibitors as anti-cancer agents and methods of making the same | 科学与工业研究会 | 2020-10-16 | — | — | CN | claimed |
| CN-107428730-B | 1,3, 5-triazinyl PI3K inhibitors as anti-cancer agents and methods of making the same | 科学与工业研究会 | 2020-10-16 | — | — | CN | disclosed |