Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18818205 | 0.90 | HRH3 (0.39) | HRH3BTK | |
| SCHEMBL18818206 | 0.90 | HRH3 (0.39) | HRH3BTK | |
| SCHEMBL28484529 | 0.81 | BTK (0.54) | HRH3BTKFFAR1 | |
| SCHEMBL18285527 | 0.79 | OPRM1 (0.40) | KCNH2BTKALDH1A1HRH1HRH4 | |
| SCHEMBL29471042 | 0.76 | OPRM1 (0.46) | KCNH2ALDH1A1KDM4EUSP2HSD17B10 | |
| SCHEMBL28490621 | 0.74 | HRH3 (0.40) | HRH3GRIN2BALDH1A1SMN1; SMN2FAP | |
| SCHEMBL18285610 | 0.73 | BTK (0.54) | HRH3BTK | |
| SCHEMBL30111801 | 0.72 | HTR6 (0.40) | BTKALDH1A1HRH1HRH4OPRM1 | |
| SCHEMBL15711153 | 0.71 | PRMT5 (0.40) | HRH3KCNH2BTKALDH1A1 | |
| SCHEMBL28491911 | 0.71 | HRH3 (0.38) | HRH3GRIN2BALDH1A1FAPFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113149983-B | Tyrosine kinase inhibitors | 普林斯匹亚生物制药公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-113149983-A | Tyrosine kinase inhibitors | 普林斯匹亚生物制药公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-106459049-B | Tyrosine kinase inhibitors | 普林斯匹亚生物制药公司 | 2020-11-27 | — | — | CN | disclosed |