Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrazine SCHEMBL25166721 | 1.00 | ALDH1A1 (0.56) | ALDH1A1LMNATDP1CYP3A4TSHR | |
| SCHEMBL19179154 | 0.94 | LMNA (0.62) | ALDH1A1LMNATDP1CYP3A4TSHR | |
| SCHEMBL642658 | 0.94 | LMNA (0.62) | ALDH1A1LMNATDP1CYP3A4TSHR | |
| SCHEMBL8918966 | 0.94 | LMNA (0.62) | ALDH1A1LMNATDP1CYP3A4TSHR | |
| SCHEMBL9204296 | 0.94 | LMNA (0.62) | ALDH1A1LMNATDP1CYP3A4TSHR | |
| SCHEMBL3401826 | 0.94 | LMNA (0.62) | ALDH1A1LMNATDP1CYP3A4TSHR | |
| SCHEMBL8381849 | 0.94 | LMNA (0.62) | ALDH1A1LMNATDP1CYP3A4TSHR | |
| SCHEMBL10582402 | 0.94 | LMNA (0.62) | ALDH1A1LMNATDP1CYP3A4TSHR | |
| SCHEMBL1769415 | 0.94 | LMNA (0.62) | ALDH1A1LMNATDP1CYP3A4TSHR | |
| SCHEMBL8571523 | 0.94 | LMNA (0.62) | ALDH1A1LMNATDP1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130674-A1 | METHOD FOR THE PRODUCTION OF POLYURETHANE COMPOSITIONS WITH A LOW ISOCYANATE MONOMER CONTENT | SIKA TECHNOLOGY AG (CH) | 2010-05-27 | — | — | US | disclosed |