SCHEMBL28484499

SCHEMBL28484499

O=C(O)Cc1cccc(-c2cccc3c2Cc2ccccc2-3)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G10 O15496 1/20 0.48
PLA2G2A P14555 1/20 0.48
SELP P16109 4/20 0.47
SELL P14151 3/20 0.47
SELE P16581 2/20 0.47
FABP4 P15090 1/20 0.45
PTGDR2 Q9Y5Y4 1/20 0.44
AKR1B1 P15121 3/20 0.43
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
GRIN3A Q8TCU5 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
ABCC4 O15439 1/20 0.42
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28491192 0.87 FFAR4 (0.46) PLA2G10PLA2G2ASELPSELLSELE
SCHEMBL28485994 0.86 ABCC4 (0.53) PTGDR2AKR1B1NPC1RAB9AABCC4
SCHEMBL28013145 0.82 PNMT (0.45) NPC1RAB9A
SCHEMBL17187933 0.82 PLA2G10 (0.60) PLA2G10PLA2G2ASELPSELLSELE
SCHEMBL3839813 0.80 PLA2G10 (0.58) PLA2G10PLA2G2ASELPSELLSELE
SCHEMBL27835839 0.80 PNMT (0.57) NPC1RAB9ALMNAENPP2
SCHEMBL27858386 0.80 PNMT (0.45) NPC1RAB9ALMNA
SCHEMBL27816253 0.80 PNMT (0.45) NPC1RAB9ALMNA
SCHEMBL30499389 0.79 PNMT (0.42) PLA2G10PLA2G2ARAB9AGAA
SCHEMBL4430289 0.78 SRD5A2 (0.58) NPC1RAB9APTGER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107429033-B Resin composition and optical lens 大阪燃气化学有限公司 2020-11-24 CN disclosed