Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.49 |
| ▸ | FDPS | P14324 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.40 |
| ▸ | TUBB | P07437 | 3/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221117 | 1.00 | TUBB1 (0.49) | TUBB1FDPSMAPTSMN1; SMN2TUBB4A | |
| SCHEMBL222288 | 0.82 | FDPS (0.46) | TUBB1FDPSMAPTSMN1; SMN2TUBB4A | |
| SCHEMBL29521713 | 0.82 | FDPS (0.46) | TUBB1FDPSMAPTSMN1; SMN2TUBB4A | |
| SCHEMBL221341 | 0.82 | FDPS (0.46) | TUBB1FDPSMAPTSMN1; SMN2TUBB4A | |
| SCHEMBL221032 | 0.82 | FDPS (0.46) | TUBB1FDPSMAPTSMN1; SMN2TUBB4A | |
| SCHEMBL1006237 | 0.81 | CYP2C9 (0.45) | TUBB1FDPSMAPTSMN1; SMN2TUBB4A | |
| SCHEMBL1006239 | 0.81 | CYP2C9 (0.45) | TUBB1FDPSMAPTSMN1; SMN2TUBB4A | |
| SCHEMBL811262 | 0.81 | CYP2C9 (0.45) | TUBB1FDPSMAPTSMN1; SMN2TUBB4A | |
| SCHEMBL4196205 | 0.81 | CYP2B6 (0.33) | TUBB1 | |
| SCHEMBL14114918 | 0.80 | TUBB1 (0.45) | TUBB1FDPSMAPTSMN1; SMN2TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723550-B2 | Process for preparing organic compounds | NOVARTIS AG (CH) | 2010-05-25 | — | — | US | disclosed |
| US-7723550-B2 | Process for preparing organic compounds | NOVARTIS AG (CH) | 2010-05-25 | — | — | US | disclosed |
| US-7723550-B2 | Process for preparing organic compounds | NOVARTIS AG (CH) | 2010-05-25 | — | — | US | disclosed |
| EP-1943205-B1 | PROCESS FOR PREPARING OF 2-ALKYL-3-ARYL-PROP-2 ENE-1-OLS | NOVARTIS AG (CH) | 2010-01-20 | — | — | EP | disclosed |
| EP-1943205-B1 | PROCESS FOR PREPARING OF 2-ALKYL-3-ARYL-PROP-2 ENE-1-OLS | NOVARTIS AG (CH) | 2010-01-20 | — | — | EP | disclosed |
| US-20090105503-A1 | Process for Preparing organic compounds | NOVARTIS PHARMA AG (CH) | 2009-04-23 | — | — | US | disclosed |
| US-20090105503-A1 | Process for Preparing organic compounds | NOVARTIS PHARMA AG (CH) | 2009-04-23 | — | — | US | disclosed |
| US-20090105503-A1 | Process for Preparing organic compounds | NOVARTIS PHARMA AG (CH) | 2009-04-23 | — | — | US | disclosed |
| EP-1943205-A1 | PROCESS FOR PREPARING OF 2-ALKYL 3-ARYL PROP-2-2ENE-1-OLS | Speedel Experimenta AG (CH) | 2008-07-16 | — | — | EP | disclosed |
| WO-2008077917-A1 | PROCESS FOR PREPARING (R OR S)-2-ALKYL-3-HETEROCYCLYL-1-PROPANOLS | NOVARTIS AG (CH) | 2008-07-03 | — | — | WO | disclosed |
| WO-2008055941-A1 | PROCESS FOR PREPARING OF 2-ALKYL-3-ARYL-PROP-2 ENE-1-OLS | SPEEDEL EXPERIMENTA AG (CH) | 2008-05-15 | — | — | WO | disclosed |
| WO-2008055941-A1 | PROCESS FOR PREPARING OF 2-ALKYL-3-ARYL-PROP-2 ENE-1-OLS | SPEEDEL EXPERIMENTA AG (CH) | 2008-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105503-A1 | Process for Preparing organic compounds | C1S, C9, C5 | TUBB1 2761/4885FDPS 1100/4885MAPT 4052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.