Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | TENT4A | Q5XG87 | 1/20 | 0.33 |
| ▸ | TENT4B | Q8NDF8 | 1/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4187233 | 0.81 | CYP2B6 (0.38) | CYP2B6TENT4ATENT4B | |
| SCHEMBL221117 | 0.81 | TUBB1 (0.49) | TUBB1 | |
| SCHEMBL2848457 | 0.81 | TUBB1 (0.49) | TUBB1 | |
| SCHEMBL4970456 | 0.78 | MEN1 (0.37) | CYP2B6TENT4ATENT4B | |
| SCHEMBL4196189 | 0.76 | FDPS (0.47) | — | |
| SCHEMBL14079852 | 0.74 | NPC1 (0.39) | CYP2B6TENT4ATENT4B | |
| SCHEMBL27200114 | 0.73 | RET (0.34) | CYP2B6TENT4ATENT4B | |
| SCHEMBL29714684 | 0.72 | CYP2B6 (0.37) | CYP2B6TENT4ATENT4B | |
| SCHEMBL21327180 | 0.72 | CYP2B6 (0.37) | CYP2B6TENT4ATENT4B | |
| SCHEMBL14080322 | 0.71 | L3MBTL1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008113835-A9 | PROCESS FOR PREPARING (R OR S)-5-{1-AZIDO-3-[6-METHOXY-5-(3-METHOXY-PROPOXY)-PYRIDIN-3-YLMETHYL]-4-METHYL-PENTYL}-3-ALKYL-DIHYDRO-FURAN-2-ONE | SPEEDEL EXPERIMENTA AG (CH) | 2009-02-19 | — | — | WO | disclosed |
| WO-2008113835-A1 | PROCESS FOR PREPARING (R OR S)-5-{1-AZIDO-3-[6-METHOXY-5-(3-METHOXY-PROPOXY)-PYRIDIN-3-YLMETHYL]-4-METHYL-PENTYL}-3-ALKYL-DIHYDRO-FURAN-2-ONE | NOVARTIS AG (CH) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008113835-A1 | PROCESS FOR PREPARING (R OR S)-5-{1-AZIDO-3-[6-METHOXY-5-(3-METHOXY-PROPOXY)-PYRIDIN-3-YLMETHYL]-4-METHYL-PENTYL}-3-ALKYL-DIHYDRO-FURAN-2-ONE | NOVARTIS AG (CH) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008113835-A1 | PROCESS FOR PREPARING (R OR S)-5-{1-AZIDO-3-[6-METHOXY-5-(3-METHOXY-PROPOXY)-PYRIDIN-3-YLMETHYL]-4-METHYL-PENTYL}-3-ALKYL-DIHYDRO-FURAN-2-ONE | NOVARTIS AG (CH) | 2008-09-25 | — | — | WO | disclosed |