Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29724622 | 0.83 | ALDH1A1 (0.59) | MAPTRXFP1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL2783065 | 0.83 | ALDH1A1 (0.59) | MAPTRXFP1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL35211812 | 0.81 | MAPT (0.56) | MAPTRXFP1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL5208264 | 0.81 | MAPT (0.56) | MAPTRXFP1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL23835828 | 0.80 | RECQL (0.51) | MAPTTP53KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL28406737 | 0.79 | MAPT (0.59) | MAPTRXFP1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL28282647 | 0.79 | ALDH1A1 (0.68) | MAPTRXFP1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL28285611 | 0.78 | MAPT (0.58) | MAPTRXFP1TP53KDM4ESMN1; SMN2 | |
| Methane SCHEMBL28285604 | 0.78 | MAPT (0.58) | MAPTRXFP1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL28479733 | 0.77 | HDAC6 (0.56) | MAPTRXFP1TP53KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108033922-B | Preparation method of 3-acyl quinoxalinone derivative | 河南工业大学 | 2020-11-06 | — | — | CN | disclosed |