Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17423807 | 0.81 | LOXL2 (0.52) | KIF11LOXL2CYP2A6ALDH1A1CYP19A1 | |
| SCHEMBL156260 | 0.79 | KIF11 (0.59) | KIF11LOXL2EPHX2CYP2A6ALDH1A1 | |
| SCHEMBL830941 | 0.78 | KIF11 (0.46) | KIF11LOXL2EPHX2CYP2A6ALDH1A1 | |
| SCHEMBL23428971 | 0.77 | KIF11 (0.44) | KIF11LOXL2EPHX2CYP2A6ALDH1A1 | |
| SCHEMBL7025558 | 0.75 | KIF11 (0.55) | KIF11LOXL2EPHX2CYP2A6ALDH1A1 | |
| SCHEMBL7025554 | 0.75 | KIF11 (0.55) | KIF11LOXL2EPHX2CYP2A6ALDH1A1 | |
| SCHEMBL8479151 | 0.75 | KIF11 (0.55) | KIF11LOXL2EPHX2CYP2A6ALDH1A1 | |
| SCHEMBL541668 | 0.73 | KIF11 (0.48) | KIF11LOXL2EPHX2CYP2A6ALDH1A1 | |
| SCHEMBL69655 | 0.73 | KIF11 (0.86) | KIF11LOXL2EPHX2CYP2A6ALDH1A1 | |
| SCHEMBL2998724 | 0.73 | KIF11 (0.64) | KIF11LOXL2EPHX2CYP2A6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111943930-B | Synthesis process of Lasmidinan | 南京三元阳普医药科技有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-111943930-A | Synthesis process of Lasmidinan | 南京三元阳普医药科技有限公司 | 2020-11-17 | — | — | CN | disclosed |