Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.60 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.48 |
| ▸ | NQO2 | P16083 | 2/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27916683 | 0.91 | ALOX5 (0.60) | ALDH1A1HSD17B10CYP1B1HIF1AALOX5 | |
| SCHEMBL2848482 | 0.85 | ALDH1A1 (0.54) | ALDH1A1HSD17B10CYP1B1HIF1AALOX5 | |
| SCHEMBL2849156 | 0.85 | ALDH1A1 (0.54) | ALDH1A1HSD17B10CYP1B1HIF1AALOX5 | |
| SCHEMBL15366577 | 0.84 | ALOX5 (0.62) | ALDH1A1HSD17B10CYP1B1HIF1AALOX5 | |
| SCHEMBL170247 | 0.84 | ALOX5 (0.62) | ALDH1A1HSD17B10CYP1B1HIF1AALOX5 | |
| SCHEMBL6684079 | 0.84 | ALOX5 (0.62) | ALDH1A1HSD17B10CYP1B1HIF1AALOX5 | |
| SCHEMBL28353300 | 0.84 | ALOX5 (0.62) | ALDH1A1HSD17B10CYP1B1HIF1AALOX5 | |
| SCHEMBL29349888 | 0.84 | ALOX5 (0.62) | ALDH1A1HSD17B10CYP1B1HIF1AALOX5 | |
| SCHEMBL25411836 | 0.84 | ALDH1A1 (0.70) | ALDH1A1HSD17B10CYP1B1HIF1AALOX5 | |
| SCHEMBL31171124 | 0.84 | ALDH1A1 (0.70) | ALDH1A1HSD17B10CYP1B1HIF1AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993123-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-03-31 | — | — | US | disclosed |
| US-20100327270-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-12-30 | — | — | US | disclosed |
| EP-2240425-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009100925-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100327270-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, ELAVL1, EPCAM | ALDH1A1 336/4885HSD17B10 2767/4885CYP1B1 836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.