SCHEMBL28485690

SCHEMBL28485690

NC(=O)C1=CC=CC=NC=N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23833210 0.82
SCHEMBL27617110 0.81 ADORA3 (0.30)
SCHEMBL29638783 0.73
SCHEMBL29768627 0.68
SCHEMBL29440550 0.64
SCHEMBL7855060 0.63
SCHEMBL28485691 0.61
SCHEMBL3843322 0.58
SCHEMBL629378 0.58
SCHEMBL629380 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107709305-B Novel compound 葛兰素史克知识产权开发有限公司 2020-09-29 CN claimed
CN-114728006-A Methods of treating coronavirus infection 苏州亚盛药业有限公司 2022-07-08 CN disclosed
CN-107709305-B Novel compound 葛兰素史克知识产权开发有限公司 2020-09-29 CN disclosed