Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28902447 | 0.86 | NPC1 (0.44) | ALDH1A1KDM4EMAPTLMNANPC1 | |
| SCHEMBL28482763 | 0.85 | MAPT (0.49) | ALDH1A1KDM4EMAPTLMNANPC1 | |
| SCHEMBL28489346 | 0.84 | CACNA1F (0.41) | ALDH1A1KDM4EMAPTLMNAHPGD | |
| SCHEMBL28493048 | 0.81 | NPC1 (0.43) | ALDH1A1MAPTNPC1KMT2AMEN1 | |
| SCHEMBL8011878 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTLMNAHPGD | |
| SCHEMBL3527114 | 0.77 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPTLMNAHPGD | |
| SCHEMBL550633 | 0.76 | KMT2A (0.52) | ALDH1A1KDM4EMAPTLMNAHPGD | |
| SCHEMBL11090216 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTLMNAHPGD | |
| SCHEMBL6609952 | 0.74 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTLMNAHPGD | |
| SCHEMBL27559505 | 0.73 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651286-B | High-selectivity synthesis method of 4- (4-aminophenyl) morpholine-3-one | 新发药业有限公司 | 2020-08-11 | — | — | CN | disclosed |