Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3527114 | 0.84 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPTLMNAHPGD | |
| SCHEMBL550633 | 0.83 | KMT2A (0.52) | ALDH1A1KDM4EMAPTLMNAHPGD | |
| SCHEMBL27798676 | 0.83 | SLC6A3 (0.50) | ALDH1A1KDM4EMAPTLMNAKMT2A | |
| SCHEMBL27652798 | 0.80 | MAPT (0.54) | ALDH1A1KDM4EMAPTLMNAHPGD | |
| SCHEMBL8770261 | 0.79 | HTR2A (0.45) | ALDH1A1KDM4EMAPTLMNAKMT2A | |
| SCHEMBL2761732 | 0.79 | SLC6A3 (0.48) | ALDH1A1KDM4EMAPTLMNAHPGD | |
| SCHEMBL11090216 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTLMNAHPGD | |
| SCHEMBL6608478 | 0.79 | ITGA4 (0.43) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL2761873 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTLMNAHPGD | |
| SCHEMBL27686943 | 0.78 | SMN1; SMN2 (0.41) | ALDH1A1MAPTLMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100482660-C | Flouroquinolone-oxazolidone derivative, composition, preparation method and application thereof | SHANGHAI INST PHARM INDUSTRY (CN) | 2009-04-29 | — | — | CN | disclosed |
| CN-101054374-A | Flouroquinolone-oxazolidone derivative, composition, preparation method and application thereof | SHANGHAI INST PHARM INDUSTRY (CN) | 2007-10-17 | — | — | CN | disclosed |
| EP-1448536-A1 | CYCLOPROPYL-CONTAINING OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2004-08-25 | — | — | EP | disclosed |
| US-6686363-B2 | EFFECTIVE AGAINST MULTI-RESISTANT BACTERIA | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2004-02-03 | — | — | US | disclosed |
| US-20030225107-A1 | CYCLOPROPYL CONTAINING OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | MERCK SHARP & DOHME CORP. | 2003-12-04 | — | — | US | disclosed |
| WO-2003048136-A1 | CYCLOPROPYL HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2003-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225107-A1 | CYCLOPROPYL CONTAINING OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | ALAD, OXA1L, ECI1 | ALDH1A1 824/4885KDM4E 3364/4885MAPT 3655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.