Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | MC4R | P32245 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL18249600 | 1.00 | KDM4E (0.33) | KDM4ECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL18249577 | 0.91 | — | — | |
| Oxalic Acid SCHEMBL28501234 | 0.86 | CCR5 (0.34) | KDM4ECHRM2CHRM4CHRM5CHRM1 | |
| Oxalic Acid SCHEMBL20164088 | 0.86 | CCR5 (0.34) | KDM4ECHRM2CHRM4CHRM5CHRM1 | |
| Oxalic Acid SCHEMBL18249573 | 0.83 | CES2 (0.37) | KDM4EDPP4ALDH1A1L3MBTL1RIPK1 | |
| Oxalic Acid SCHEMBL28496501 | 0.83 | CES2 (0.37) | KDM4EDPP4ALDH1A1L3MBTL1RIPK1 | |
| SCHEMBL18249570 | 0.81 | DRD3 (0.34) | — | |
| Oxalic Acid SCHEMBL18249652 | 0.79 | CCR5 (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL18249564 | 0.78 | CA1 (0.32) | — | |
| SCHEMBL18249635 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107646031-B | Azetidine derivatives as modulators of cortical catecholaminergic neurotransmission | 综合研究实验室瑞典股份公司 | 2020-11-17 | — | — | CN | disclosed |