SCHEMBL28486182

SCHEMBL28486182

CCC(C)OC(=O)COCCN

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA13 Q8N1Q1 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
EPHX2 P34913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21373956 0.83 ALDH1A1 (0.38) TDP1CA12CA1CA2CA3
SCHEMBL28292932 0.82 TDP1 (0.40) TDP1
SCHEMBL7900784 0.79 TDP1 (0.38) TDP1
SCHEMBL19917421 0.79 TDP1 (0.38) TDP1
SCHEMBL19822064 0.76 CA12 (0.41) CA12CA1CA2CA3CA4
SCHEMBL15593349 0.76
SCHEMBL8785000 0.76
SCHEMBL19821869 0.74 EPHX2 (0.34) CA12CA1CA2CA3CA4
SCHEMBL19822062 0.73 CYP1A2 (0.53) CA12CA1CA2CA3CA4
SCHEMBL26412892 0.73 ALDH1A1 (0.35) TDP1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109651286-B High-selectivity synthesis method of 4- (4-aminophenyl) morpholine-3-one 新发药业有限公司 2020-08-11 CN disclosed