Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900784 | 0.96 | TDP1 (0.38) | TDP1LMNAMAPTTSHRCYP2D6 | |
| SCHEMBL7651937 | 0.85 | TDP1 (0.43) | TDP1LMNAMAPTTSHRCYP2D6 | |
| SCHEMBL28486182 | 0.82 | TDP1 (0.33) | TDP1 | |
| SCHEMBL11115364 | 0.82 | LMNA (0.46) | TDP1LMNAMAPTTSHRCYP2D6 | |
| SCHEMBL645857 | 0.81 | TDP1 (0.41) | TDP1LMNAMAPTTSHRCYP2D6 | |
| SCHEMBL26419587 | 0.81 | LMNA (0.48) | TDP1LMNAMAPTTSHRCYP2D6 | |
| SCHEMBL5606265 | 0.81 | LMNA (0.48) | TDP1LMNAMAPTTSHRCYP2D6 | |
| SCHEMBL8100476 | 0.79 | TDP1 (0.40) | TDP1LMNAMAPTTSHRCYP2D6 | |
| SCHEMBL12588874 | 0.79 | TSHR (0.43) | TDP1LMNAMAPTTSHRALDH1A1 | |
| SCHEMBL27854310 | 0.79 | TDP1 (0.40) | TDP1LMNAMAPTTSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651286-B | High-selectivity synthesis method of 4- (4-aminophenyl) morpholine-3-one | 新发药业有限公司 | 2020-08-11 | — | — | CN | disclosed |
| CN-109651286-A | A kind of highly selective 4-(4- aminophenyl) morpholine -3- ketone synthetic method | 新发药业有限公司 | 2019-04-19 | — | — | CN | disclosed |