Fluorene

Fluorene

SCHEMBL28486262

OC(Oc1ccccc1)Oc1ccccc1.c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.43
MAOA P21397 2/20 0.42
MAPT P10636 3/20 0.40
LMNA P02545 2/20 0.40
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CYP1A2 P05177 3/20 0.38
CYP3A4 P08684 2/20 0.38
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
MMP12 P39900 1/20 0.36
MMP13 P45452 1/20 0.36
ADRA2A P08913 1/20 0.36
SLC6A2 P23975 1/20 0.36
HTR2C P28335 1/20 0.36
SLC6A4 P31645 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL6682184 0.85 SRD5A2 (0.41) SRD5A2MAOAMAPTLMNAKDM4E
Fluorene SCHEMBL23094101 0.85 SRD5A2 (0.41) SRD5A2MAOAMAPTLMNAKDM4E
SCHEMBL10596047 0.81 LTA4H (0.45) SRD5A2LMNAKDM4EALDH1A1CYP1A2
Fluorene SCHEMBL22501634 0.80 SRD5A2 (0.40) SRD5A2MAOAMAPTLMNAKDM4E
Fluorene SCHEMBL27934493 0.76 MAOA (0.65) SRD5A2MAOAMAPTLMNAKDM4E
Fluorene SCHEMBL28031599 0.76 MAOA (0.65) SRD5A2MAOAMAPTLMNAKDM4E
Fluorene SCHEMBL14118022 0.76 MAOA (0.65) SRD5A2MAOAMAPTLMNAKDM4E
Fluorene SCHEMBL8378972 0.76 MAOA (0.65) SRD5A2MAOAMAPTLMNAKDM4E
Fluorene SCHEMBL28818074 0.73 MAOA (0.62) SRD5A2MAOAMAPTLMNAKDM4E
Fluorene SCHEMBL27843738 0.73 MAOA (0.62) SRD5A2MAOAMAPTLMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111886315-A Sealing material for display element, cured product thereof, frame sealing material for organic EL element, and surface sealing material for organic EL element 三井化学株式会社 2020-11-03 CN disclosed