Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GRM8 | O00222 | 3/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.38 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL480910 | 0.85 | KMT2A (0.47) | GRM8GRM1GRM7GRM4GRM5 | |
| SCHEMBL4592036 | 0.81 | KMT2A (0.46) | LMNAGRM8GRM1GRM7GRM4 | |
| Propionamide SCHEMBL28290130 | 0.77 | GRM8 (0.48) | GRM8GRM1GRM7GRM4GRM5 | |
| SCHEMBL10481361 | 0.75 | KMT2A (0.44) | GRM8GRM1GRM7GRM4GRM5 | |
| SCHEMBL7174908 | 0.74 | GRM8 (0.39) | GRM8GRM1GRM7GRM4GRM5 | |
| SCHEMBL6125509 | 0.73 | KMT2A (0.51) | GRM8GRM1GRM7GRM4GRM5 | |
| Coumarin SCHEMBL1707602 | 0.73 | CA12 (0.80) | CA12CA1CA2CA3CA4 | |
| Coumarin SCHEMBL2197947 | 0.73 | CA12 (0.62) | CA12CA1CA2CA3CA4 | |
| Coumarin SCHEMBL28966037 | 0.73 | CA12 (0.62) | CA12CA1CA2CA3CA4 | |
| Coumarin SCHEMBL28477322 | 0.73 | CA12 (0.62) | CA12CA1CA2CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111920797-A | Application of 3-aryl benzofuranone compound | 山东省医学科学院药物研究所（山东省抗衰老研究中心、山东省新技术制药研究所） | 2020-11-13 | — | — | CN | disclosed |