Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 4/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.48 |
| ▸ | GRM7 | Q14831 | 4/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.48 |
| ▸ | GRM5 | P41594 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL480910 | 0.90 | KMT2A (0.47) | GRM8GRM1GRM7GRM4GRM5 | |
| SCHEMBL4592036 | 0.86 | KMT2A (0.46) | GRM8GRM1GRM7GRM4GRM5 | |
| SCHEMBL10481361 | 0.80 | KMT2A (0.44) | GRM8GRM1GRM7GRM4GRM5 | |
| SCHEMBL7174908 | 0.79 | GRM8 (0.39) | GRM8GRM1GRM7GRM4GRM5 | |
| SCHEMBL6125509 | 0.78 | KMT2A (0.51) | GRM8GRM1GRM7GRM4GRM5 | |
| Coumarin SCHEMBL28486266 | 0.77 | CA12 (0.47) | GRM8GRM1GRM7GRM4GRM5 | |
| SCHEMBL21436988 | 0.77 | GRM8 (0.51) | GRM8GRM1GRM7GRM4GRM5 | |
| SCHEMBL28597652 | 0.76 | KMT2A (0.47) | GRM8GRM1GRM7GRM4GRM5 | |
| SCHEMBL28596988 | 0.76 | KMT2A (0.47) | GRM8GRM1GRM7GRM4GRM5 | |
| SCHEMBL7455266 | 0.76 | CES2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109694362-B | 3-arylbenzofuranone propionamide compound, composition formed by same, preparation method and application thereof | 江苏裕事达新材料科技有限责任公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-109694362-B | 3-arylbenzofuranone propionamide compound, composition formed by same, preparation method and application thereof | 江苏裕事达新材料科技有限责任公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-109694362-A | 3- arylben-zofuranone propanamide compounds, its composition constituted and its preparation method and application | 优缔新材料科技(苏州)有限公司 | 2019-04-30 | — | — | CN | disclosed |