SCHEMBL480910

SCHEMBL480910

CCCCCC1C(=O)Oc2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
GRM8 O00222 4/20 0.46
GRM1 Q13255 4/20 0.46
GRM7 Q14831 4/20 0.46
GRM4 Q14833 4/20 0.46
GRM5 P41594 2/20 0.46
MAPT P10636 1/20 0.44
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4592036 0.95 KMT2A (0.46) KMT2AMEN1GRM8GRM1GRM7
Propionamide SCHEMBL28290130 0.90 GRM8 (0.48) KMT2AMEN1GRM8GRM1GRM7
SCHEMBL10481361 0.88 KMT2A (0.44) KMT2AMEN1GRM8GRM1GRM7
SCHEMBL7174908 0.87 GRM8 (0.39) KMT2AMEN1GRM8GRM1GRM7
SCHEMBL6125509 0.86 KMT2A (0.51) KMT2AMEN1GRM8GRM1GRM7
Coumarin SCHEMBL28486266 0.85 CA12 (0.47) KMT2AMEN1GRM8GRM1GRM7
SCHEMBL21436988 0.85 GRM8 (0.51) KMT2AMEN1GRM8GRM1GRM7
SCHEMBL28597652 0.84 KMT2A (0.47) KMT2AMEN1GRM8GRM1GRM7
SCHEMBL28596989 0.84 KMT2A (0.47) KMT2AMEN1GRM8GRM1GRM7
SCHEMBL28596988 0.84 KMT2A (0.47) KMT2AMEN1GRM8GRM1GRM7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 535 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115157734-B BOPP adhesive tape manufacturing process 福建友谊胶粘带集团有限公司 2024-04-16 CN claimed
US-11905484-B2 Fullerene-containing lubricating oil composition and method for producing same RESONAC CORPORATION (JP) 2024-02-20 US claimed
CN-115157734-A BOPP adhesive tape manufacturing process 福建友谊胶粘带集团有限公司 2022-10-11 CN claimed
CN-109503477-B Triarylmethane compound and high-efficiency catalytic synthesis method thereof 湖南大学 2021-10-22 CN claimed
WO-2021112957-A1 ARYL BENZOFURANONE- STABILIZED POLYCARBONATE COMPOSITIONS, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2021-06-10 WO claimed
CN-111920797-A Application of 3-aryl benzofuranone compound 山东省医学科学院药物研究所(山东省抗衰老研究中心、山东省新技术制药研究所) 2020-11-13 CN claimed
US-10703734-B2 3-aryl-benzofuranone compound and composition formed therefrom EUTEC CHEMICAL CO., LTD. (TW) 2020-07-07 US claimed
CN-110900914-A Production and vulcanization process of rubber cathode insulating strip 云南大泽电极科技股份有限公司 2020-03-24 CN claimed
CN-109971075-A A kind of manufacture craft of adhesive tape BOPP film 武汉友发包装科技有限公司 2019-07-05 CN claimed
CN-109923162-A Low emission scorch inhibitors for polyurethane foams 范德比尔特化工有限公司 2019-06-21 CN claimed
EP-0981530-B1 COMPOUNDS ON THE BASIS OF POLYALKYL-1-OXA-DIAZASPIRODECANE COMPOUNDS CLARIANT GMBH (DE) 2003-02-19 EP claimed
CN-1388815-A Aromatic monovinyl resin composition A & M STYRENE CO LTD (JP) 2003-01-01 CN claimed
US-6497956-B1 Structural recycled plastic lumber BIOLUMBER INC. 2002-12-24 US claimed
US-6420461-B1 Compounds based on polyalkyl-1-oxadiazaspirodecane compounds CLARIANT GMBH (DE) 2002-07-16 US claimed
EP-0839623-B1 Stabiliser combination for rotomolding process CIBA SC HOLDING AG (CH) 2001-01-31 EP claimed
EP-1004623-A1 Aryl thioacetals useful as stabilizers in polymeric materials GREAT LAKES CHEMICAL CORPORATION (US) 2000-05-31 EP claimed
EP-0981530-A1 COMPOUNDS ON THE BASIS OF POLYALKYL-1-OXA-DIAZASPIRODECANE COMPOUNDS Clariant GmbH (DE) 2000-03-01 EP claimed
WO-1998051690-A1 COMPOUNDS ON THE BASIS OF POLYALKYL-1-OXA-DIAZASPIRODECANE COMPOUNDS CLARIANT GMBH (DE) 1998-11-19 WO claimed
CN-1195671-A Compositions stabilized with tertiary amine oxides GEN ELECTRIC (US) 1998-10-14 CN claimed
EP-0839623-A1 Stabiliser combination for rotomolding process Ciba SC Holding AG (CH) 1998-05-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10703734-B2 3-aryl-benzofuranone compound and composition formed therefrom ZNF436-AS1, CDK16, WASF2 KMT2A 3785/4885MEN1 3075/4885GRM8 3375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.