SCHEMBL2848627

SCHEMBL2848627

CC(OCCN)OC(C(=O)O)C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.44
FABP5 Q01469 3/20 0.43
FABP7 O15540 2/20 0.43
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
CASP3 P42574 1/20 0.38
TLR2 O60603 2/20 0.37
EPHX2 P34913 1/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
MDM4 O15151 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL570371 0.88 KMT2A (0.49) KMT2AFABP5FABP7PPARGPPARA
SCHEMBL29203790 0.81 KMT2A (0.45) KMT2AFABP5FABP7PPARGPPARA
SCHEMBL415413 0.81 KMT2A (0.45) KMT2AFABP5FABP7PPARGPPARA
SCHEMBL17339044 0.81 KMT2A (0.45) KMT2AFABP5FABP7PPARGPPARA
SCHEMBL29203732 0.81 KMT2A (0.45) KMT2AFABP5FABP7PPARGPPARA
SCHEMBL16583993 0.80 KMT2A (0.51) KMT2AFABP5FABP7CASP3TLR2
SCHEMBL148347 0.78 ALDH1A1 (0.43) KMT2A
SCHEMBL2040433 0.78 KMT2A (0.50) KMT2AFABP5FABP7CASP3EPHX2
SCHEMBL3794900 0.75 KMT2A (0.55) KMT2ACASP3TLR2EPHX2MDM4
SCHEMBL14717015 0.75 PPARG (0.46) KMT2AFABP5FABP7PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673113-B1 IMPLANTS WITH ATTACHED SILYLATED THERAPEUTIC AGENTS SMART TECH LP (US) 2010-12-29 EP disclosed
US-7737251-B2 Long lasting glucagon-like peptide 2 (GLP-2) for the treatment of gastrointestinal diseases and disorders CONJUCHEM BIOTECHNOLOGIES INC. (CA) 2010-06-15 US disclosed
US-20090312259-A1 LONG LASTING GLUCAGON-LIKE PEPTIDE 2 (GLP-2) FOR THE TREATMENT OF GASTROINTESTINAL DISEASES AND DISORDERS CONJUCHEM BIOTECHNOLOGIES INC. 2009-12-17 US disclosed
EP-1980572-A1 Long lasting glucagon-like peptide 2 (GLP-2) for the treatment of gastrointestinal diseases and disorders ConjuChem Biotechnologies Inc. (CA) 2008-10-15 EP disclosed
EP-1360202-B1 LONG LASTING GLUCAGON-LIKE PEPTIDE 2 (GLP-2) FOR THE TREATMENT OF GASTROINTESTINAL DISEASES AND DISORDERS CONJUCHEM BIOTECHNOLOGIES INC (CA) 2008-05-21 EP disclosed
US-7268113-B2 Long lasting growth hormone releasing factor derivatives CONJUCHEM BIOTECHNOLOGIES INC. (CA) 2007-09-11 US disclosed
US-20060286140-A1 Implants with attached silylated therapeutic agents SMART TECH LP 2006-12-21 US disclosed
US-20060217304-A1 Long lasting glucagon-like peptide 2 (GLP-2) for the treatment of gastrointestinal diseases and disorders CONJUCHEM, LLC 2006-09-28 US disclosed
US-7112567-B2 Long lasting glucagon-like peptide 2 (glp-2) for the treatment of gastrointestinal diseases and disorders CONJUCHEM INC. (CA) 2006-09-26 US disclosed
EP-1673113-A2 IMPLANTS WITH ATTACHED SILYLATED THERAPEUTIC AGENTS Wickstrom, Eric (US) 2006-06-28 EP disclosed
WO-2005027990-A2 IMPLANTS WITH ATTACHED SILYLATED THERAPEUTIC AGENTS UNIV JEFFERSON (US) 2005-03-31 WO disclosed
US-20040248782-A1 Long lasting glucagon-like peptide2(glp-2)for the treatment of gastrointestinal diseases and disorders CONJUCHEM, LLC 2004-12-09 US disclosed
EP-1360202-A2 LONG LASTING GLUCAGON-LIKE PEPTIDE 2 (GLP-2) FOR THE TREATMENT OF GASTROINTESTINAL DISEASES AND DISORDERS ConjuChem, Inc. (CA) 2003-11-12 EP disclosed
EP-1355941-A2 LONG LASTING GROWTH HORMONE RELEASING FACTOR DERIVATIVES ConjuChem, Inc. (CA) 2003-10-29 EP disclosed
US-20030073630-A1 Long lasting growth hormone releasing factor derivatives CONJUCHEM, LLC 2003-04-17 US disclosed
WO-2002066511-A2 LONG LASTING GLUCAGON-LIKE PEPTIDE 2 (GLP-2) FOR THE TREATMENT OF GASTROINTESTINAL DISEASES AND DISORDERS CONJUCHEM INC. (CA) 2002-08-29 WO disclosed
WO-2002062844-A2 LONG LASTING GROWTH HORMONE RELEASING FACTOR DERIVATIVES CONJUCHEM INC. (CA) 2002-08-15 WO disclosed