Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.63 |
| ▸ | CTSS | P25774 | 1/20 | 0.63 |
| ▸ | SIRT2 | Q8IXJ6 | 14/20 | 0.62 |
| ▸ | SIRT1 | Q96EB6 | 11/20 | 0.62 |
| ▸ | SIRT3 | Q9NTG7 | 6/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17694108 | 0.91 | SIRT2 (0.68) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL7133785 | 0.89 | SIRT2 (0.66) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL14157704 | 0.87 | SIRT2 (0.67) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL14157706 | 0.87 | SIRT2 (0.67) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL17435163 | 0.87 | SIRT2 (0.67) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL18907026 | 0.87 | SIRT2 (0.67) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL17244715 | 0.87 | SIRT5 (0.62) | SIRT2SIRT1SIRT3 | |
| SCHEMBL8766104 | 0.86 | CTSL (0.76) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL18907028 | 0.85 | FOLH1 (0.72) | SIRT2SIRT1SIRT3 | |
| SCHEMBL14157463 | 0.85 | FOLH1 (0.72) | SIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107082747-B | Compounds for targeted drug delivery and enhancing siRNA activity | 日东电工株式会社 | 2020-11-20 | — | — | CN | disclosed |