SCHEMBL2848640

SCHEMBL2848640

CC(C)(C)P(c1ccccc1-c1cccc(N)c1-c1ccccc1P(C(C)(C)C)C(C)(C)C)C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.42
ADORA2A P29274 3/20 0.38
ALDH1A1 P00352 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PDK2 Q15119 1/20 0.35
HSPA1A P0DMV8 1/20 0.33
PABPC1 P11940 1/20 0.33
FGR P09769 1/20 0.33
PIM1 P11309 1/20 0.33
MAOA P21397 1/20 0.33
CSNK1A1 P48729 1/20 0.33
CSNK1D P48730 1/20 0.33
DYRK1A Q13627 1/20 0.33
HIPK2 Q9H2X6 1/20 0.33
CSNK1G1 Q9HCP0 1/20 0.33
DPP4 P27487 1/20 0.32
CD44 P16070 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CYP3A4 P08684 2/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29492107 0.81 ALDH1A1 (0.30) ALDH1A1L3MBTL1HSD17B10
SCHEMBL333685 0.81 ALDH1A1 (0.30) ALDH1A1L3MBTL1HSD17B10
SCHEMBL646868 0.80 MYC (0.42) ALDH1A1L3MBTL1PDK2DPP4CD44
SCHEMBL2851164 0.80 PTPRC (0.46) PTPRCADORA2AALDH1A1L3MBTL1PDK2
SCHEMBL2851947 0.76 PTPRC (0.46) PTPRCADORA2AALDH1A1L3MBTL1PDK2
SCHEMBL2850828 0.76 PTPRC (0.42) PTPRCADORA2AALDH1A1L3MBTL1PDK2
SCHEMBL2850111 0.74 PTPRC (0.43) PTPRCADORA2AALDH1A1L3MBTL1PDK2
SCHEMBL2620734 0.72 TOP1 (0.42) ADORA2AALDH1A1PDK2PIM1SMN1; SMN2
SCHEMBL196673 0.72 NPC1 (0.36) ALDH1A1CYP3A4TSHRSMN1; SMN2
SCHEMBL29548615 0.72 NPC1 (0.36) ALDH1A1CYP3A4TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100093920-A1 NICKEL CATALYST SYSTEM FOR THE PREPARATION OF HIGH CIS POLYBUTADIENE BRIDGESTONE CORPORATION (JP) 2010-04-15 US claimed
US-8436111-B2 Nickel catalyst system for the preparation of high CIS polybutadiene BRIDGESTONE CORPORATION (JP) 2013-05-07 US disclosed
US-20100093920-A1 NICKEL CATALYST SYSTEM FOR THE PREPARATION OF HIGH CIS POLYBUTADIENE BRIDGESTONE CORPORATION (JP) 2010-04-15 US disclosed