Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | FGR | P09769 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.34 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30842815 | 0.85 | ALDH1A1 (0.54) | ADORA2ACYP3A4TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL30842821 | 0.85 | ALDH1A1 (0.54) | ADORA2ACYP3A4TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL29230460 | 0.85 | ALDH1A1 (0.54) | ADORA2ACYP3A4TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL1768448 | 0.81 | CYP3A4 (0.48) | CYP3A4TDP1DRD1ESR1ESR2 | |
| SCHEMBL29620625 | 0.80 | CYP3A4 (0.52) | CYP3A4TDP1ALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL5403788 | 0.80 | CYP3A4 (0.52) | CYP3A4TDP1ALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL1120987 | 0.80 | CYP3A4 (0.58) | CYP3A4TDP1DRD1ESR1ESR2 | |
| SCHEMBL16094790 | 0.80 | CYP3A4 (0.39) | CYP3A4TDP1DRD1ESR1ESR2 | |
| Bromide SCHEMBL17963057 | 0.78 | CYP3A4 (0.50) | CYP3A4TDP1ALDH1A1L3MBTL1HSD17B10 | |
| Iodide SCHEMBL8511390 | 0.78 | CYP3A4 (0.50) | CYP3A4TDP1ALDH1A1L3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093920-A1 | NICKEL CATALYST SYSTEM FOR THE PREPARATION OF HIGH CIS POLYBUTADIENE | BRIDGESTONE CORPORATION (JP) | 2010-04-15 | — | — | US | claimed |
| US-8436111-B2 | Nickel catalyst system for the preparation of high CIS polybutadiene | BRIDGESTONE CORPORATION (JP) | 2013-05-07 | — | — | US | disclosed |
| US-20100093920-A1 | NICKEL CATALYST SYSTEM FOR THE PREPARATION OF HIGH CIS POLYBUTADIENE | BRIDGESTONE CORPORATION (JP) | 2010-04-15 | — | — | US | disclosed |